peak and trough. The highest and lowest concentrations of a drug in plasma. Measurement of peak and trough drug levels are used to determine whether an intravenously administered medication is consistently within therapeutic range.
For webmasters: peak and trough specimens. serum samples collected to determine the level of an antibiotic or other pharmaceutic agent in the blood. Peak specimens, which represent the highest level, are generally collected ½ hour after the dose is given intravenously or …
Jan 31, 2019 · Peak and trough are methods used to establish the effectiveness of a drug. Peak is drawing the serum blood levels after the drug is administered as it distributes rapidly and reaches its peak in therapeutic range. Trough is drawing the serum blood levels right before the next dose.
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Definition of peak-to-trough. The stage of the business or market cycle from the end of a period of growth (peak) into declining activity and contraction until it hits its ultimate cyclical bottom (trough). This is the change in a data measure – e.g., an asset price or economic statistic – …
A trough is the stage of the economy’s business cycle that marks the end of a period of declining business activity and the transition to an expansion. The business cycle is the upward and downward movement of gross domestic product and consists of recessions and expansions that end in peaks and troughs. BREAKING DOWN ‘Trough’.
Jan 26, 2019 · The vancomycin peak and trough represent two extremes in terms of the levels of concentration of this antibiotic in a patient’s bloodstream. At the peak, large amounts are circulating, and at the trough, the levels fall very low.
The peak of a wave and the trough of a wave are always twice the wave’s amplitude apart from each other. The part of the wave half way in between the peak and the trough is called the baseline. Complicated wave forms (like the sound waves of music) can be made by adding up sine waves of different frequencies.
trough – a long narrow shallow receptacle. receptacle – a container that is used to put or keep things in. cradle, rocker – a trough that can be rocked back and forth; used by gold miners to shake auriferous earth in water in order to separate the gold.
[trawf, trof or, sometimes, trawth, troth] See more synonyms for trough on Thesaurus.com. noun. a long, narrow, open receptacle, usually boxlike in shape, used chiefly to hold water or food for animals. any of several similarly shaped receptacles used for various commercial or household purposes.
Trough level. A trough level is contrasted with a “peak level”, which is the highest level of the medicine in the body, and the “average level”, which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for …
17 Reading: The Business Cycle: Definition and Phases. The Business Cycle. The term “business cycle” (or economic cycle or boom-bust cycle) refers to economy-wide fluctuations in production, trade, and general economic activity. troughs of the business cycle. An expansion is the period from a trough to a peak, and a recession as the
Therapeutic Drugs – Optimal Time to Draw Samples the collection and testing of specimens for trough and peak levels is necessary. The trough level is the lowest concentration in the patient’s bloodstream, therefore, the specimen should be collected just prior to administration of the drug. The peak level is the highest concentration of a
Definition of Trough in the Financial Dictionary – by Free online English dictionary and encyclopedia. What is Trough? Meaning of Trough as a finance term. What does Trough mean in finance? BEA economist Bruce Grimm found that the four monthly measures do not fully agree with the committee’s peak and trough months.